Open Face Flow Cells

Open face flow cells enable repeated and reliable sealing to substrates, such as microarrays and functionalized glass surfaces. These devices typically consist of the following three elements: fluidic fittings, an optical window with drilled access holes and a permanently bonded gasket seal. All three elements are custom configured to best match users’ applications.  A common use for these devices is in microarray manufacturing process control, when wet reactions are used for quality control testing.  In this case, an open face flow cell consisting of a gasketed optical window with fluidic connections is fixtured on top of the microarray. Once the quality control reaction has run its course, the open face flow cell is removed and cleaned for the next reaction. CiDRA® Precision Services, LLC’s BioGasket™ Technology is ideal for this application because it forms permanent covalent bonds with glass windows to create fluidic channels that stand up to the harshest use profiles.  No more dealing with O-rings leaking or falling off makes for efficient and user friendly processes and satisfied customers.

Applications:

  • Hybridization Chambers
  • Process Control
  • Bioagent Detection
  • Sequencing